Alternative approaches for medical countermeasures to biological and chemical terrorism and warfare

Food for Thought ... Alternative Approaches for Medical Countermeasures to Biological and Chemical Terrorism and Warfare

Countermeasures evaluation is the new kid on the block of alternative approaches. And it is a big kid that appeared suddenly: Over the last six months three funding opportunities in the US totaled more than $ 200 million, all with the goal of advancing the Human on a Chip concept. An alliance of US agencies is tackling the problem of evaluating drugs for which there are no patients and, hopeful...

Alternative approaches for medical countermeasures to biological and chemical terrorism and warfare.

The desire to develop and evaluate drugs as potential countermeasures for biological and chemical threats requires test systems that can also substitute for the clinical trials normally crucial for drug development. Animal models have limited predictivity for drug efficacy, as is well known from many disappointments in clinical trials. Traditional in vitro and in silico approaches are not reall...

[Chemical and biological warfare].

Scientific series Medical Aspects of Chemical and Biological Terrorism Chemical Terrorism and Traumatism

Medical Threat and Nuclear, Biological, and Chemical Warfare

a. Since World War II, the Soviet Union has represented the principal threat to the national security interests of the US. During this period, the military capability of the Soviet Armed Forces grew enormously. Starting in the later years of the 1980's, the international security environment has undergone rapid, fundamental, and revolutionary changes. The Soviet Union has disintegrated with the...